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Pharmacodynamics
A series of in vitro and in vivo trials have exemplified the probable mechanism of action of the extract of Saw palmetto.
Hypothetically, it includes::
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inhibition of type 1 and type 2 isoforms of 5α-reductase; |
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inhibition of the binding of dihydrotestosterone with the receptors of the cytosolic androgen in the prostatic cells; |
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blocking effect on α-adrenergic receptors; |
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inhibition of prolactin and proliferation of prostatic cells induced by the growth factor; |
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antiestrogenic activity, anti-inflammatory and antispasmolytic effects. |
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